2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N7811
    2-Hydroxytetracosanoic acid 544-57-0 98%
    2-Hydroxytetracosanoic acid is an ester product.
    2-Hydroxytetracosanoic acid
  • HY-N7815
    3-Hydroxytridecanoic acid 32602-69-0 98%
    3-Hydroxytridecanoic acid is an ester product.
    3-Hydroxytridecanoic acid
  • HY-N7857
    19(R)-Hydroxy-prostaglandin F2α 64625-53-2 98%
    19(R)-Hydroxy-prostaglandin F2α (19(R)-hydroxy PGF2α) is an ω-1 hydroxylase metabolite of PGF2α found in human semen. The concentration of 19(R)-Hydroxy-PGFs compounds (F2α and F1α together) in fresh human semen is about 20 μg/mL. 19(R)-Hydroxy-prostaglandin F2α exhibits no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 μM.
    19(R)-Hydroxy-prostaglandin F2α
  • HY-N7865
    1,2-Palmitolein-3-olein 107196-42-9 98%
    1,2-Palmitolein-3-olein (1,2-Dipalmitoleoyl-3-Oleoyl-rac-glycerol) is a triacylglycerol found in the fat body of bumblebees.
    1,2-Palmitolein-3-olein
  • HY-N7866
    2-Hydroxytricosanoic acid 2718-37-8 98%
    2-Hydroxytricosanoic acid is an ester product.
    2-Hydroxytricosanoic acid
  • HY-N7950
    16-Oxoalisol A 124515-98-6 98%
    16-Oxoalisol A is a triterpene in Rhizoma Alismatis. Rhizoma Alismatis is a commonly used traditional Chinese medicine (TCM). Rhizoma Alismatis can be used for the research of urinary tract diseases.
    16-Oxoalisol A
  • HY-N7988
    4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate 23414-61-1 98%
    4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate is a polyacetylene compound found in the rhizomes of Atractylodes lancea. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate inhibits human pancreatic lipase, with an IC50 of 55.67 μM and 16.7 μg/mL. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate can block the digestion of triglycerides by inhibiting the activity of human pancreatic lipase. 4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate can be used in research on obesity.
    4,6,12-Tetradecatriene8,10-diyne-1,3-diacetate
  • HY-N8007
    Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha 138989-37-4 98%
    Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha is a flavonol glycoside with no significant inhibitory activity against albumin oleate-induced lipid accumulation.
    Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha
  • HY-N8068
    Dihydrooroxylin A 18956-18-8
    Dihydrooroxylin A is an active compound. Dihydrooroxylin A can be used as a dietary supplement.
    Dihydrooroxylin A
  • HY-N8086
    Korepimedoside C 205445-00-7 98%
    Korepimedoside C (Epimedin I), a flavonol glycoside, is isolated from the aerial parts of Epimedium koreanum Nakai. Epimedium koreanum Nakai is a famous Chinese herbal medicine for the research of impotence, osteoporosis, immune suppression and cardiovascular diseases.
    Korepimedoside C
  • HY-N8087
    Epimedin K 174286-13-6 98%
    Epimedin K (Korepimedoside B), a flavonol glycoside, is isolated from the aerial parts of Epimedium koreanum Nakai. Epimedium koreanum Nakai is a famous Chinese herbal medicine for the research of impotence, osteoporosis, immune suppression and cardiovascular diseases.
    Epimedin K
  • HY-N8120
    Bisabolone oxide A 22567-38-0 98%
    Bisabolone oxide A is an α-glucosidase inhibitor.
    Bisabolone oxide A
  • HY-N8143
    Emodin-1-O-β-gentiobioside 849789-95-3 98%
    Emodin-1-O-β-gentiobioside is an anthraquinone.
    Emodin-1-O-β-gentiobioside
  • HY-N8201
    Rheumone B 2095596-67-9 98%
    Rheumone B possesses antioxidant activity.
    Rheumone B
  • HY-N8204
    Siaresinolic acid 28-O-β-D-glucopyranosyl ester 155653-86-4 98%
    Siaresinolic acid 28-O-β-D-glucopyranosyl ester possesses anti-tumor and antidiabetic effect activity.
    Siaresinolic acid 28-O-β-D-glucopyranosyl ester
  • HY-N8250
    cis-THSG 928205-59-8 98%
    cis-THSG is a selective and orally active DNA topoisomerase II inhibitor with no activity against DNA topoisomerase I. cis-THSG suppresses transcription of PEPCK. cis-THSG reduces blood glucose levels, ameliorates glucose intolerance, and alleviates insulin resistance in high fat diet-induced diabetic male CF-1 mice. cis-THSG can be used for the research of type 2 diabetes mellitus.
    cis-THSG
  • HY-N8331
    Terpendole I 167612-17-1 98%
    Terpendole I is a fungal indole diterpenoid and an ACAT inhibitor (IC50 = 145 µM). Terpendole I can be used in studies related to lipid metabolism.
    Terpendole I
  • HY-N8359
    Questinol 35688-09-6 98%
    Questinol is a palmitic acid that can be isolated from Talaromyces stipitatus. Questinol has signi?cant anti-obesity activity in zebra?sh larvae.
    Questinol
  • HY-N8523
    Vibralactone D 1251748-32-9 98%
    Vibralactone D (Compound 1) is a metabolite isolated and cultured from natural basidiomycetes Boreostereum vibrans. Vibralactone D shows weak inhibitory activity against isoenzymes of 11b-hydroxysteroid dehydrogenase (HSD) (IC50 85.7 μM).
    Vibralactone D
  • HY-N8731
    Lutein dipalmitate 547-17-1 98%
    Lutein dipalmitate (Helenien), a Lutein ester, is a dominant compound in Lutein supplement.
    Lutein dipalmitate
Cat. No. Product Name / Synonyms Application Reactivity